Related Experiment Video
Updated: Aug 8, 2026

Analysis of Raw and Processed Cyperi Rhizoma Samples Using Liquid Chromatography-Tandem Mass Spectrometry in Rats with Primary Dysmenorrhea
Published on: December 23, 2022
[Effects of slenderstyle Acanthopanax root-bark on cyclooxygenase]
Jian-Bo Qiu1, Qi-Cai Long, Mei-Cun Yao
1GuangZhou QiaoGuang Pharmaceutical Co. Ltd. , Guangzhou 510140, China.
Objective:
To explore the effects of slenderstyle acanthopanax root-bark on cyclooxygenase in vivo and in vitro.
Method:
Contents of 6-keto-PGF1alpha in bovine aorta endothelial cells, PGE2 in mouse abdominal macrophages, and 6-keto-PGF1alpha in rat stomach tissue were determined. The ulcer index in rat gastric mucosa was measured.
Result:
COX-1 and COX-2 were inhibited by slenderstyle acanthopanax root-bark, and the inhibitive rate of COX-2 was higher than that of COX-1 at the same concentration. Necrotic injuries in health gastric mucosa were not produced, but the injuries previously induced by the ethanol worsened.
Conclusion:
One of the antirheumatic mechanisms of slender-root-bark might probably be mediating through inhibition of cyclooxygenase. style acanthopanax
Related Concept Videos
Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
Drugs for Treatment of Ulcerative Colitis in IBD