Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Understanding obsessive-compulsive disorder: focus on decision making.

Paolo Cavedini1, Alessandra Gorini, Laura Bellodi

  • 1San Raffaele Scientific Institute, Department of Neuropsychiatric Sciences, Universitá Vita-Salute San Raffaele, Faculty of Psychology, 20 Via Stamir D'Aneona, 20127 Milan, Italy. cavedini.paolo@hsr.it

Neuropsychology Review
|May 19, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mind over lungs: the impact of coping strategies on pulmonary rehabilitation outcomes.

European journal of physical and rehabilitation medicine·2026
Same author

Affairs of the heart: couples coping with cardiac rehabilitation.

Psychology & health·2026
Same author

Study design of the InTakeCare trial: a digital health solution to monitor and improve medication adherence in hypertensive patients.

European heart journal. Digital health·2026
Same author

Cardiologists' attitudes toward psychological care: a national survey on perceptions, collaboration and barriers.

Journal of cardiovascular medicine (Hagerstown, Md.)·2026
Same author

Behavioural withdrawal during an acute stress test as a marker of psychobiological vulnerability in hereditary angioedema.

Frontiers in immunology·2026
Same author

Robot-assisted therapy following stroke: what effects on quality of life, cognitive and psychosocial outcomes? A systematic review.

Journal of rehabilitation medicine·2026
Same journal

Use and Psychometric Properties of the MoCA in Spain: a Systematic Review With Meta-Analysis and Meta-Regression.

Neuropsychology review·2026
Same journal

Health Outcomes Following Traumatic Brain Injury: An Umbrella Review.

Neuropsychology review·2026
Same journal

A Systematic Review of Functional Brain Imaging Studies in Neurofibromatosis 1.

Neuropsychology review·2026
Same journal

Editorial March, 2026 Neuropsychology Review.

Neuropsychology review·2026
Same journal

Efficacy of Cognitive Training for Treating Cancer-related Cognitive Impairment: Systematic Review and Meta-analysis by Cognitive Domain.

Neuropsychology review·2026
Same journal

Immersive Virtual Reality in Neuropsychological Assessment of Acquired Brain Injury: a Systematic Review and Meta-Analysis.

Neuropsychology review·2026
See all related articles

Obsessive-compulsive disorder (OCD) is linked to neurobiological issues, particularly in fronto-subcortical brain circuits. Research suggests decision-making deficits may contribute to OCD

Area of Science:

  • Neuroscience
  • Psychiatry
  • Cognitive Psychology

Background:

  • Obsessive-compulsive disorder (OCD) is increasingly understood to involve neurobiological abnormalities.
  • Key brain regions implicated include the fronto-subcortical circuit (orbitofrontal cortex, basal ganglia, thalamus).
  • Patients with OCD exhibit executive functioning deficits and reduced cognitive-behavioral flexibility.

Purpose of the Study:

  • To explore the role of decision-making deficits in obsessive-compulsive disorder (OCD).
  • To understand how impaired decision-making contributes to the heterogeneity of OCD symptoms and behaviors.

Main Methods:

  • Review of current neurobiological and neuropsychological findings related to OCD.
  • Focus on decision-making as a critical executive function.

Related Experiment Videos

  • Analysis of studies linking fronto-subcortical function to cognitive deficits in OCD.

    • Main Results:

    • Neurobiological abnormalities, particularly in fronto-subcortical circuits, are central to OCD.
    • Executive functioning deficits, including decision-making, are evident in OCD patients.
    • Impaired ability to balance immediate versus long-term rewards may be a factor.

    Conclusions:

    • Decision-making deficits are significant in understanding OCD's clinical and behavioral heterogeneity.
    • Further research is needed to fully elucidate the role of decision-making in OCD's evolution.
    • Findings have implications for therapeutic strategies targeting cognitive flexibility in OCD.