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Informatic Analysis of Sequence Data from Batch Yeast 2-Hybrid Screens
Published on: June 28, 2018
[DNAStat, version 1.0--a software package for processing a genetic profile database and for biostatistical
1Z Zakładu Orzecznictwa Sadowo-Lekarskiego i Ubezpieczeniowego Katedry Medycyny Sadowej Uniwersytetu Medycznego w Lodzi. J.Berent@eranet.pl
Abstract:
The application of DNA studies to the administration of justice has led to the necessity of developing appropriate computer programs. Such programs must address two critical problems, i.e. the broadly understood data processing and archivization, and biostatistical calculations. This paper discusses DNAStat 1.0, a program that enables its user to 1) create and process an individual database; 2) analyze biological evidence by calculating the unconditional f and conditional p(X/X) profile frequency, with the possibility of taking into account the inbreeding (coancestry) coefficient, as well as setting the minimum allele frequency; 3) analyze paternity cases by calculating the paternity index PI and probability of paternity W for full and motherless trios, with the possibility of taking into account the silent allele frequency and prior probability.
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