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[Pseudo-tumoral neuro-Behçet's disease]
M Darmoul1, M Habib Bouhaouala, H Smida
1Unité de Neurochirurgie, Hôpital des FSI, La Marsa, Tunisie. mehdi.darmoul@laposte.net
Revue Neurologique
|May 20, 2006
Summary
Neuro-Behçet disease can rarely present as a brain tumor. This case highlights the importance of considering Behçet's disease in patients with neurological symptoms mimicking tumors.
Area of Science:
- Neurology
- Immunology
- Rheumatology
Background:
- Central nervous system (CNS) involvement in Behçet's disease affects 10-30% of patients.
- Pseudo tumoral presentation of neuro-Behçet's disease is uncommon.
- Behçet's disease is a rare multisystem inflammatory disorder.
Observation:
- A 38-year-old male with a history of folliculitis presented with acute headache, right hemiplegia, aphasia, and altered consciousness.
- Neuroradiological imaging revealed a pseudo tumoral lesion in the left capsulo-thalamic region extending to the cerebral peduncle.
- The patient's symptoms suggest a rare pseudo tumoral manifestation of neuro-Behçet's disease.
Findings:
- The patient's clinical presentation and neuroimaging findings mimicked a brain tumor.
- Treatment with corticosteroids and immunosuppressants led to clinical improvement.
- This case underscores the diagnostic challenge posed by pseudo tumoral neuro-Behçet's disease.
Implications:
- Clinicians should consider neuro-Behçet's disease in the differential diagnosis of brain tumors, especially in patients with a history of inflammatory conditions.
- Early diagnosis and appropriate immunosuppressive therapy are crucial for managing pseudo tumoral neuro-Behçet's disease.
- Further research is needed to understand the pathogenesis and optimize treatment strategies for this rare neurological complication.

