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Understanding and exploiting the endogenous interleukin-10/STAT3-mediated anti-inflammatory response

Peter J Murray1

  • 1Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, TN 38105, USA. peter.murray@stjude.org

Current Opinion in Pharmacology
|May 23, 2006
PubMed
Summary

Interleukin-10 (IL-10) is crucial for controlling inflammation by blocking pro-inflammatory genes. While direct IL-10 therapy has limitations, understanding its receptor signaling offers new avenues for anti-inflammatory drug development.

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