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Annually recurring erythema annulare centrifugum: a distinct entity?
M Pilar García Muret1, Ramon M Pujol, Anna M Gimenez-Arnau
1Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. mgarciam@hsp.santpau.es
Journal of the American Academy of Dermatology
|May 23, 2006
Summary
Annually recurring erythema annulare centrifugum, a rare distinct clinical entity, presents with persistent, predictable seasonal flare-ups. Lesions mimic classic erythema annulare centrifugum but recur yearly for decades without identifiable triggers.
Area of Science:
- Dermatology
- Clinical Medicine
Background:
- Erythema annulare centrifugum (EAC) is a reactive erythema characterized by annular lesions.
- Classic EAC typically presents as transient, non-specific eruptions.
Observation:
- Four patients exhibited EAC with consistent annual and seasonal recurrences over many years.
- Lesions were clinically and histopathologically identical to classic superficial EAC.
- No specific precipitating factors or associated symptoms were identified.
Findings:
- The observed variant demonstrates a distinct pattern of chronic, predictable recurrence.
- This suggests a potential distinct clinical entity within the EAC spectrum.
- The condition shows spontaneous regression after variable durations.
Implications:
- Highlights a rare, under-recognized variant of erythema annulare centrifugum.
- Emphasizes the need for considering chronic, seasonal EAC in differential diagnoses.
- Further research is warranted to elucidate the pathogenesis of this recurrent eruption.
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