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Related Experiment Videos

Baroreflex function in hypertension: consequences for antihypertensive therapy.

Guido Grassi1, Fosca Quarti Trevano, Gino Seravalle

  • 1Clinica Medica, Dipartimento di Medicina Clinica, Prevenzione e Biotecnologie Sanitarie, Ospedale San Gerardo dei Tintori, Università Milano-Bicocca, Via Pergolesi 33, 20052 Monza, Milan, Italy. guido.grassi@unimib.it

Progress in Cardiovascular Diseases
|May 23, 2006
PubMed
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High blood pressure alters cardiovascular reflex control, impacting organ damage. Antihypertensive drugs targeting neural control are crucial for effective hypertension treatment and preventing complications.

Area of Science:

  • Cardiovascular physiology
  • Neuropharmacology
  • Hypertension research

Background:

  • Hypertension significantly alters neural cardiovascular control mechanisms.
  • These alterations contribute to target organ damage in hypertensive individuals.
  • Understanding neural control is vital for managing hypertension.

Purpose of the Study:

  • To review changes in cardiovascular reflex control in hypertension.
  • To examine the impact of antihypertensive drugs on neural cardiovascular control.
  • To discuss drug effects in both uncomplicated and complicated hypertension.

Main Methods:

  • Review of existing literature on hypertension and cardiovascular control.
  • Analysis of studies in animal models and human subjects.

Related Experiment Videos

  • Examination of data on various classes of antihypertensive medications.

    • Main Results:

    • Hypertension profoundly affects cardiovascular reflex control through direct and indirect pathways.
    • Neural cardiovascular control plays a role in hypertension-related target organ damage.
    • Antihypertensive drugs demonstrate varied effects on neural cardiovascular control.

    Conclusions:

    • Modulating neural cardiovascular control is a key therapeutic strategy in hypertension.
    • Understanding drug effects on neural control is essential for optimizing treatment.
    • Further research is needed to fully elucidate these complex interactions.