Loxoscelism
Related Experiment Video
Updated: Aug 8, 2026

Assessing Lysosomal Alkalinization in the Intestine of Live Caenorhabditis elegans
Published on: April 13, 2018
David L Swanson1, Richard S Vetter
1Department of Dermatology, Mayo Clinic, Scottsdale, AZ 85259, USA. swanson.david@mayo.edu
Abstract:
Loxoscelism (bites by spiders of the genus Loxosceles) is the only proven arachnological cause of dermonecrosis. Although Loxosceles spiders can be found worldwide, their distribution is heavily concentrated in the Western Hemisphere, particularly the tropical urban regions of South America. Although Loxosceles bites are usually mild, they may ulcerate or cause more severe, systemic reactions. These injuries mostly are due to sphingomyelinase D in the spider venom. There is no proven effective therapy for Loxosceles bites, although many therapies are reported in the literature.
More Related Videos
Related Concept Videos
Lysosomal Hydrolases
Pleiotropy
Lysosomes
Toxoplasmosis
Necrosis
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become anucleated and die, but their...
Leishmaniasis

