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Medical evaluation and treatment of urolithiasis
Julie A Nicoletta1, Marc B Lande
1Division of Pediatric Nephrology, Department of Pediatrics, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14624, USA. julie_nicoletta@urmc.rochester.edu
Insights
Pediatric nephrolithiasis (kidney stones) affects many children, often linked to underlying conditions. Early evaluation and tailored treatments are key for managing pediatric kidney stones effectively.
Area of Science:
- Pediatric Nephrology
- Urology
- Metabolic Disorders
Background:
- Nephrolithiasis (kidney stones) is a significant cause of pediatric hospital admissions in the US.
- Approximately 75% of children with kidney stones have an identifiable predisposition.
- Understanding these predispositions is crucial for effective management.
Purpose of the Study:
- To review the causes and associated disease states of pediatric nephrolithiasis.
- To outline the initial and metabolic evaluation protocols for affected children.
- To describe treatment modalities for various pediatric kidney stone types.
Main Methods:
- Literature review of causes, evaluations, and treatments for pediatric nephrolithiasis.
- Analysis of predisposition factors in pediatric stone formation.
- Synthesis of current diagnostic and therapeutic approaches.
Main Results:
- Identified various causes and disease states contributing to pediatric kidney stones.
- Detailed initial and metabolic workup strategies for children with nephrolithiasis.
- Summarized treatment options based on stone type.
Conclusions:
- Pediatric nephrolithiasis necessitates a comprehensive approach, including identifying underlying causes.
- Thorough metabolic evaluation is essential for guiding treatment and preventing recurrence.
- Effective management strategies exist for diverse pediatric kidney stone conditions.
Abstract:
Nephrolithiasis is responsible for 1 in 1000 to 1 in 7600 pediatric hospital admissions annually throughout the United States. Seventy-five percent of children with nephrolithiasis have an identifiable predisposition to stone formation. This article reviews the different causes and disease states associated with nephrolithiasis in the pediatric population. The initial evaluation and the metabolic evaluation of children with nephrolithiasis are reviewed. Treatment modalities for the different stone types are also described.
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