Related Experiment Video
Updated: May 25, 2025

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
Published on: May 3, 2018
Youth Blood Pressure and Target Organ Injury Markers: The SHIP AHOY Study
Gilad Hamdani1, Elaine M Urbina2, Stephen R Daniels3
1Schneider Children's Medical Center, Petah Tikvah, Israel (G.H.).
Adolescent hypertension, even when mild, is linked to early signs of organ damage. Higher blood pressure levels and specific hypertension types (white-coat, masked, sustained) correlate with more markers of cardiovascular injury in young people.
Area of Science:
- Cardiology
- Pediatrics
- Public Health
Background:
- Adolescent hypertension is a growing concern.
- Subclinical target organ injury is associated with hypertension in adolescents.
- Understanding blood pressure thresholds and their impact on organ injury is crucial.
Purpose of the Study:
- To determine if different blood pressure thresholds are associated with an increasing number of target organ injury markers in healthy adolescents.
- To investigate the relationship between ambulatory blood pressure phenotypes and target organ injury.
Main Methods:
- 244 adolescents (mean age 15.5 years) were categorized into low, mid, and high-risk blood pressure groups based on clinic and ambulatory readings.
- Ambulatory blood pressure phenotypes included normotensive, white-coat, masked, and sustained hypertension.
- Target organ injury was assessed through left ventricular mass, cardiac function, and vascular stiffness.
Main Results:
- 31.2% of participants had at least one target organ injury marker.
- The number of injury markers increased with higher blood pressure risk groups (P=0.02 for clinic BP, P<0.001 for ambulatory BP).
- White-coat, masked, and sustained hypertension were significantly associated with more injury markers compared to normotension (P<0.001).
Conclusions:
- Elevated clinic and ambulatory blood pressure are independently linked to increased subclinical cardiovascular injury markers in adolescents.
- Specific ambulatory blood pressure phenotypes (white-coat, masked, sustained hypertension) are associated with a greater number of injury markers.
- These findings highlight the importance of monitoring blood pressure and identifying hypertension phenotypes in adolescents to prevent cardiovascular complications.
Related Concept Videos
Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Factors affecting Blood pressure
Physiological Factors:
Hypertension and Regulation of Blood Pressure
Pre-Procedural Guidelines for Assessing Blood Pressure
Errors occurring during blood pressure monitoring
Several factors...
Measurement of Blood Pressure

