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Updated: May 12, 2026

Evaluation of Cancer Stem Cell Migration Using Compartmentalizing Microfluidic Devices and Live Cell Imaging
Published on: December 23, 2011
Brain tumour stem cells
Angelo L Vescovi1, Rossella Galli, Brent A Reynolds
1Department of Biotechnology and Biosciences, University of Milan Bicocca, Milan 20126, Italy. vescovi@tin.it
Abstract:
The dogma that the genesis of new cells is a negligible event in the adult mammalian brain has long influenced our perception and understanding of the origin and development of CNS tumours. The discovery that new neurons and glia are produced throughout life from neural stem cells provides new possibilities for the candidate cells of origin of CNS neoplasias. The emerging hypothesis is that alterations in the cellular and genetic mechanisms that control adult neurogenesis might contribute to brain tumorigenesis, thereby allowing the identification of new therapeutic strategies.
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