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Related Experiment Videos

Assessment of olfactory function.

Thomas Hummel1, Antje Welge-Lüssen

  • 1Smell & Taste Clinic, Department of Otorhinolaryngology, University of Dresden edical School ('Technische Universität Dresden'), Dresden, Germany; bDepartment f Otorhinolaryngology, University of Basel, Basel, Switzerland.

Advances in Oto-Rhino-Laryngology
|May 31, 2006
PubMed
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This study reviews methods for assessing human chemosensory functions, focusing on psychophysical tests like odor identification and thresholds. These techniques are crucial for understanding olfactory dysfunction and patient quality of life.

Area of Science:

  • Neuroscience
  • Sensory Science
  • Clinical Research

Background:

  • Human chemosensory functions, particularly olfaction, are vital for quality of life.
  • Assessing these functions is crucial for diagnosing and managing related disorders.
  • Various methods exist, ranging from subjective psychophysical tests to objective physiological measures.

Purpose of the Study:

  • To provide a comprehensive overview of available techniques for investigating human chemosensory functions.
  • To highlight the clinical utility and limitations of different assessment methods.
  • To discuss the role of these techniques in evaluating olfactory dysfunction and its impact.

Main Methods:

  • Psychophysical measures: odor identification, discrimination, thresholds, memory, and retronasal perception.

Related Experiment Videos

  • Questionnaires assessing quality of life and subjective olfactory dysfunction.
  • Objective measures: chemosensory event-related potentials, EEG changes, electroolfactogram, imaging, and respiration.
  • Clinical application primarily relies on psychophysical tests and event-related potentials.

    • Main Results:

    • Psychophysical techniques are most frequently employed in clinical settings for olfactory assessment.
    • Questionnaires help evaluate the impact of olfactory dysfunction on patients' quality of life.
    • Objective measures like chemosensory event-related potentials aid in result interpretation but require further standardization for widespread clinical use.

    Conclusions:

    • A variety of methods exist for evaluating human chemosensory functions, with psychophysical tests being predominant clinically.
    • Objective measures offer complementary data but need further standardization for broader clinical adoption.
    • Continued research and standardization are essential to enhance the clinical utility of diverse chemosensory assessment techniques.