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Updated: Aug 8, 2026

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas
Published on: September 13, 2019
[Spermatocytic seminoma with rhabdomyosarcomatous contingent]
Inès Chelly1, Amina Mekni, Mohamed Mrad Gargouri
1Service d'Anapatomologie, Hôpital La Rabta, Tunis, Tunisie.
Introduction:
Spermatocytic seminoma is a relatively rare testicular tumour, not associated with another germ-cell tumour component and characterized by a favourable prognosis. However, discovery of a sarcomatous contingent modifies the prognosis.
Material And Method:
The authors report the case of a 50-year-old man with a history of right testicular swelling for 4 years, gradually increasing in size without vaginal effusion. Tumour markers were normal. Ultrasound demonstrated a very large semi-solid semi-cystic testicular mass with a long axis of 14 cm. Orchidectomy was performed.
Result:
Histological examination and immunohistochemistry of the orchidectomy specimen concluded on spermatocytic seminoma associated with a rhabdomyosarcomatous component.
Conclusion:
Only 12 cases of spermatocytic seminoma with sarcomatous component have been reported in the literature The presence of a sarcomatous component confers a very poor prognosis to spermatocytic seminoma.
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