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Related Experiment Videos

Pressure relieving support surfaces (PRESSURE) trial: cost effectiveness analysis.

Cynthia Iglesias1, Jane Nixon, Gillian Cranny

  • 1Department of Health Sciences, University of York, York YO10 5DD.

BMJ (Clinical Research Ed.)
|June 3, 2006
PubMed
Summary
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Alternating pressure mattresses are more cost-effective for preventing hospital-acquired pressure ulcers than overlays. These mattresses offer greater patient benefits and are more likely to be cost-saving.

Area of Science:

  • Healthcare economics
  • Clinical nursing research
  • Medical device efficacy

Background:

  • Hospital-acquired pressure ulcers pose a significant clinical and economic burden.
  • Effective prevention strategies are crucial for patient outcomes and healthcare resource management.
  • Support surfaces play a key role in pressure ulcer prevention protocols.

Purpose of the Study:

  • To compare the cost-effectiveness of alternating pressure mattresses versus alternating pressure overlays for preventing pressure ulcers in hospitalized patients.
  • To evaluate the economic impact and clinical benefits of different pressure-relieving support surfaces.

Main Methods:

  • A multicentre UK-based pragmatic randomised controlled trial (PRESSURE trial) involving 1971 participants across 11 hospitals.

Related Experiment Videos

  • Cost-effectiveness analysis alongside the trial, utilizing Kaplan-Meier estimates for time to pressure ulcer development and total treatment costs.
  • Intention-to-treat analysis to assess outcomes between the two types of support surfaces.

    • Main Results:

    • Alternating pressure mattresses demonstrated lower average costs (283.63 pounds sterling per patient) primarily due to reduced hospital length of stay.
    • A delay in pressure ulcer development was observed with mattresses (10.64 days), though not statistically significant.
    • Cost-effectiveness acceptability curves indicated an 80% probability that mattresses are more cost-saving than overlays.

    Conclusions:

    • Alternating pressure mattresses are likely more cost-effective for preventing pressure ulcers in hospitalized patients compared to alternating pressure overlays.
    • The findings suggest mattresses offer better value and patient acceptability, supporting their use in clinical practice.
    • Further economic evaluations can inform procurement decisions for pressure-relieving support surfaces.