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Noma neonatorum.

Tushar B Parikh1, R N Nanavati, R H Udani

  • 1Department of Neonatology, King Edward Memorial Hospital and Seth G S Medical College, Mumbai, India. tbparikh@rediffmail.com

Indian Journal of Pediatrics
|June 3, 2006
PubMed
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Noma Neonatorum, a severe neonatal condition, typically involves gangrene and Pseudomonas aeruginosa. This case highlights a rare instance of Noma Neonatorum linked to E. coli sepsis in newborns.

Area of Science:

  • Neonatal Medicine
  • Infectious Diseases
  • Pediatric Surgery

Background:

  • Noma Neonatorum is a rare, destructive gangrenous infection affecting neonates, primarily premature and low birth weight infants.
  • The condition typically involves mucocutaneous junctions of the oral, nasal, and anal areas, potentially extending to eyelids and scrotum.
  • Pseudomonas aeruginosa septicemia is the commonly associated bacterial infection.

Observation:

  • This report details a unique case of Noma Neonatorum in a neonate.
  • The observed infection was associated with Escherichia coli (E. coli) sepsis.

Findings:

  • This is the first documented case of Noma Neonatorum associated with E. coli sepsis.
  • The findings expand the known microbial spectrum of this severe neonatal condition.

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Implications:

  • Highlights the need for broader microbiological investigation in Noma Neonatorum beyond Pseudomonas aeruginosa.
  • Suggests E. coli as a potential causative agent in neonatal gangrenous infections.
  • Informs clinical management and diagnostic approaches for Noma Neonatorum.