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In vitro release of elements from prosthodontic base metal alloys: effect of protein-containing biologic environments
Neslihan Efeoglu1, Berran Ozturk, Canan Coker
1Department of Restorative Dentistry, Leeds Dental Institute, University of Leeds, United Kingdom. n.efeoglu@leeds.ac.uk
Purpose:
This study aimed to investigate the release of nickel, copper, zinc, cadmium, magnesium, and lead from prosthodontic base metal alloys into protein-containing biologic solutions.
Materials And Methods:
Dissolution experiments were conducted in either 3% Dulbecco's Modified Eagle Medium or 3% bovine serum albumin solutions for 7 weeks.
Results:
The protein-containing dissolution solutions and dissolution time did not have a significant effect on release of elements from the alloys (Kruskal-Wallis, P > .05).
Conclusions:
The amount of the released elements was well below the dietary intake levels of these elements. This study is important given the widespread use of the base metal alloys and the continuing public concerns/questions regarding the health benefits/risks associated with these materials.
