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06:51
A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
Multifocal venous malformations: two interesting case presentations
Orbit (Amsterdam, Netherlands)
|June 7, 2006
Summary
This study reports two rare cases of multifocal venous vascular malformations (VVMs) affecting the orbit, head, neck, and limbs. These findings highlight a previously undocumented association of VVMs across diverse body regions.
Area of Science:
- Vascular Surgery
- Radiology
- Dermatology
Background:
- Venous vascular malformations (VVMs) can affect various body regions.
- Previous literature has described VVMs in the orbit, head, and neck.
Observation:
- Two cases of multifocal, low-flow VVMs involving the orbit, head, neck, and peripheral limbs are presented.
- Patients exhibited distensible lesions in response to Valsalva maneuver or dynamic maneuvers.
- Imaging revealed bilateral orbital VVMs and associated developmental venous anomalies in the brain in one case.
Findings:
- This is the first report documenting the association of orbital, cervicofacial, and peripheral limb VVMs.
- The presented cases demonstrate a rare multifocal VVM pattern.
- VVMs were characterized as low-flow and benign, with symptoms primarily due to mass effect.
Implications:
- These findings expand the understanding of VVM distribution and presentation.
- Highlights the importance of considering widespread VVMs in diagnosis.
- Suggests conservative management for VVMs without sight-threatening complications.
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