Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Aneurysmal bone cyst.

William M Mendenhall¹, Robert A Zlotecki, C Parker Gibbs

¹Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA. mendewil@shands.ufl.edu

American Journal of Clinical Oncology

|June 7, 2006

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A modified Delphi consensus on tenosynovial giant cell tumour and giant cell tumour of bone : a report from the Birmingham Orthopaedic Oncology Meeting (BOOM).

The bone & joint journal·2026

Same author

Perineurioma-like EMA-positive calvarial neoplasms: clinicopathological study of eight cases.

Histopathology·2026

Same author

Does This Imaging Make Me Look NFATC2 ? The Value of Radiologic-pathologic Correlation in NFATC2 -rearranged Sarcomas of Bone.

The American journal of surgical pathology·2026

Same author

Consensus recommendations in the management of jaw (gnathic) osteosarcoma.

Cancer·2026

Same author

Pulmonary Metastasectomy Versus Stereotactic Beam Radiation Therapy for Sarcoma Pulmonary Metastasis: A Retrospective Cohort Study.

Cureus·2025

Same author

Benign Bone Forming (Osteoblastic) Tumors.

Surgical pathology clinics·2025

Same journal

Upper Extremity Lymphedema: Performance of a Risk Prediction Model in Women Undergoing Surgery for Breast Cancer.

American journal of clinical oncology·2026

Same journal

Executive Summary of the American Radium Society (ARS) Appropriate Use Criteria (AUC) for the Use of Radiation in the Prevention and Treatment of Heterotopic Ossification (HO).

American journal of clinical oncology·2026

Same journal

Stereotactic Body Radiation Therapy Combined With Immune Checkpoint Inhibitors in Unresectable Hepatocellular Carcinoma: A Comprehensive Single-Arm Meta-Analysis Approach.

American journal of clinical oncology·2026

Same journal

Emergence of Single-Week Adjuvant Radiation Therapy for Early-Stage Breast Cancer in the United States.

American journal of clinical oncology·2026

Same journal

Early Versus Delayed Pancreatic Enzyme Replacement Therapy After Pancreatic Cancer Surgery: A Real-World Cohort Study.

American journal of clinical oncology·2026

Same journal

Early Economic and Patient-Centered Outcomes Before Spine Metastases Radiation Therapy From an Ongoing Phase II Randomized Controlled Trial.

American journal of clinical oncology·2026

See all related articles

Aneurysmal bone cysts (ABCs) are rare bone tumors. Surgery is the primary treatment, with most patients cured after one or more operations, while low-dose radiotherapy offers an alternative for select cases.

Area of Science:

Orthopedic Oncology
Skeletal Pathology
Tumor Biology

Background:

Aneurysmal bone cysts (ABCs) represent 1-2% of all primary bone tumors.
Typically diagnosed in the first two decades of life with a slight female predominance.
Understanding the natural history and treatment nuances is crucial for patient management.

Purpose of the Study:

To elucidate the natural history of aneurysmal bone cysts.
To review and discuss current treatment modalities for ABCs.
To analyze patient outcomes following various therapeutic interventions.

Main Methods:

Comprehensive review of relevant scientific literature.
Analysis of epidemiological data and clinical presentations of ABCs.

Related Experiment Videos

Evaluation of treatment efficacy and recurrence rates.

Main Results:

Curettage is the most common surgical approach, achieving local control in 70-90% of cases.
Surgical excision offers high local control rates.
Low-dose radiotherapy (26-30 Gy) demonstrates approximately 90% local control for aggressive or recurrent ABCs.

Conclusions:

Surgical intervention, including curettage and excision, remains the cornerstone of ABC treatment.
Most patients achieve a cure through surgical means, often requiring multiple procedures.
Low-dose radiotherapy is an effective option for incompletely resectable, aggressive, or recurrent ABCs.