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Published on: August 18, 2022
Linear basal cell carcinoma: A distinct clinical entity
I Mavrikakis1, R Malhotra, D Selva
1Corneo Plastic Unit, The Queen Victoria Hospital, Holtye Road, East Grinstead, RH19 3DZ, UK.
Linear basal cell carcinoma (BCC) presents uniquely along skin tension lines. Margin-controlled excision is recommended due to its aggressive behavior and subclinical extension, impacting surgical planning.
Area of Science:
- Dermatology
- Plastic Surgery
- Oncology
Background:
- Basal cell carcinoma (BCC) is the most common skin cancer.
- Linear BCC is a rare morphoeic variant with distinct clinical characteristics.
- Limited literature exists on linear BCC within plastic surgery.
Purpose of the Study:
- To define linear basal cell carcinoma (BCC) as a distinct clinical entity.
- To highlight the significance of linear BCC in plastic surgery literature.
- To review reported cases and analyze clinical and histological features.
Main Methods:
- A comprehensive literature search was performed using Medline and PubMed.
- 33 reported cases of linear BCC were identified and analyzed.
- Data on tumor site, histological subtype, and excision margins were extracted.
Main Results:
- The periocular region was the most common site (49%).
- Nodular BCC was the most frequent histological subtype (50%).
- Excision margins were often insufficient, with none achieving complete excision using 2mm or 4mm margins in the cases analyzed.
Conclusions:
- Linear BCC is a distinct clinical entity requiring specific management considerations.
- Its presentation along relaxing skin tension lines suggests increased subclinical extension.
- Margin-controlled excision is advised due to aggressive behavior and potential for incomplete resection.
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