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Determination of neurochemicals in biological fluids by using an automated high-performance liquid chromatographic
V Rizzo1, G M d'Eril, G Achilli
1Servizio Analisi Chimico Cliniche e Neurochimica, IRCCS Istituto Neurologico C. Mondino, Università di Pavia, Italy.
Journal of Chromatography
|January 4, 1991
Abstract:
The chromatographic separation of 33 neurochemicals was achieved by using a combined gradient of organic modifier, pH and counter-ion. A secondary separation of unresolved analytes was obtained by using electrochemical detection with a coulometric array of sixteen electrodes. The stability of the analytes was studied and data on analytical performance are reported in addition to a list of neurochemicals detected in a normal plasma sample.