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The DERP: is it an effective methodology?
1Blue Cross and Blue Shield of Minnesota, Eagan, Minnesota, USA. Al_Heaton@bluecrossmn.com
Health Affairs (Project Hope)
|June 8, 2006
Summary
The Drug Effectiveness Review Project (DERP) faces challenges impacting its effectiveness. This perspective examines DERP issues and suggests alternative methods for drug comparisons to improve evidence-based decision-making for pharmacy and therapeutics committees.
Area of Science:
- Pharmacoeconomics
- Health Technology Assessment
- Drug Policy
Background:
- The Drug Effectiveness Review Project (DERP) aims to provide evidence for drug selection.
- Pharmacy and Therapeutics (P&T) committees rely on DERP for formulary decisions.
- Existing drug review processes face limitations in timeliness and evidence depth.
Discussion:
- Key barriers include the need for more timely and substantial evidence for new drugs.
- Alternative methodologies are proposed for comparing drugs with limited direct comparators.
- The DERP process has influenced changes in drug review practices for P&T committees.
Key Insights:
- DERP faces inherent challenges that affect its overall effectiveness.
- The demand for robust evidence often outpaces the availability of comparative data.
- Innovative approaches are necessary to evaluate new drugs effectively.
Outlook:
- Continuous exploration of methodologies can enhance drug review processes.
- Developing more effective metrics for drug evaluation is crucial.
- Achieving a perfect drug review system remains an ongoing objective.
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