Related Experiment Video

Updated: Aug 8, 2026

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

Incidence and pathogenic effect of Streptococcus pseudopneumoniae

Colette Harf-Monteil1, Carole Granello, Cécile Le Brun

  • 1Institute of Bacteriology, UPRES-EA 3432, Louis Pasteur University, Strasbourg University Hospital, Strasbourg, France. colette.harf-monteil@medecine.u-strasbg.fr

Journal of Clinical Microbiology
|June 8, 2006
PubMed

Insights

Streptococcus pseudopneumoniae has a low incidence in clinical samples. This bacterium shows potential for causing disease, as demonstrated in a mouse sepsis model.

Area of Science:

  • Microbiology
  • Bacterial Pathogenesis

Background:

  • Streptococcus pseudopneumoniae is a bacterium that can be mistaken for Streptococcus pneumoniae.
  • Accurate identification is crucial for understanding its role in human infections.

Purpose of the Study:

  • To determine the frequency of S. pseudopneumoniae in clinical isolates.
  • To assess the pathogenic potential of S. pseudopneumoniae.

Main Methods:

  • Phenotypic identification methods were used.
  • DNA-DNA hybridization confirmed bacterial identity.
  • A mouse peritonitis/sepsis model was employed to evaluate pathogenicity.

Main Results:

  • S. pseudopneumoniae was found at a low incidence, accounting for 1 in 120 pneumococcal isolates.
  • The mouse model indicated a potential pathogenic effect of S. pseudopneumoniae.

Conclusions:

  • S. pseudopneumoniae is an infrequently encountered bacterium in clinical settings.
  • Further research is warranted to fully elucidate the clinical significance and pathogenic mechanisms of S. pseudopneumoniae.

More Related Videos

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling08:25

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling

Published on: April 7, 2015

Investigating the Effects of Probiotics on Pneumococcal Colonization Using an In Vitro Adherence Assay09:20

Investigating the Effects of Probiotics on Pneumococcal Colonization Using an In Vitro Adherence Assay

Published on: April 28, 2014

Related Concept Videos

Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
Streptococcal Pharyngitis01:27

Streptococcal Pharyngitis

Streptococcal pharyngitis, commonly known as “strep throat,” is an acute infection of the oropharyngeal tissues caused by the Gram‑positive Group A Streptococcus (Streptococcus pyogenes). Transmission occurs primarily through respiratory droplets expelled during coughing, sneezing, or talking.Mechanisms of Host Entry and Immune EvasionUpon entering the host, S. pyogenes adheres to the mucosal epithelial cells of the pharynx via surface proteins, notably lipoteichoic acid and the antiphagocytic...
Determinants of Bacterial Pathogenicity and Virulence01:20

Determinants of Bacterial Pathogenicity and Virulence

Pathogenic bacteria employ a variety of strategies to establish infections, including the secretion of extracellular enzymes that act as potent virulence factors. These enzymes facilitate bacterial colonization of host tissues and help evade immune surveillance. By targeting structural components of host tissues and interfering with immune mechanisms, these enzymes play a pivotal role in disease progression.Extracellular Enzymes Facilitating Tissue Invasion: Several bacterial pathogens secrete...