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Incidence and pathogenic effect of Streptococcus pseudopneumoniae
Colette Harf-Monteil1, Carole Granello, Cécile Le Brun
1Institute of Bacteriology, UPRES-EA 3432, Louis Pasteur University, Strasbourg University Hospital, Strasbourg, France. colette.harf-monteil@medecine.u-strasbg.fr
Journal of Clinical Microbiology
|June 8, 2006
Summary
Streptococcus pseudopneumoniae has a low incidence in clinical samples. This bacterium shows potential for causing disease, as demonstrated in a mouse sepsis model.
Area of Science:
- Microbiology
- Bacterial Pathogenesis
Background:
- Streptococcus pseudopneumoniae is a bacterium that can be mistaken for Streptococcus pneumoniae.
- Accurate identification is crucial for understanding its role in human infections.
Purpose of the Study:
- To determine the frequency of S. pseudopneumoniae in clinical isolates.
- To assess the pathogenic potential of S. pseudopneumoniae.
Main Methods:
- Phenotypic identification methods were used.
- DNA-DNA hybridization confirmed bacterial identity.
- A mouse peritonitis/sepsis model was employed to evaluate pathogenicity.
Main Results:
- S. pseudopneumoniae was found at a low incidence, accounting for 1 in 120 pneumococcal isolates.
- The mouse model indicated a potential pathogenic effect of S. pseudopneumoniae.
Conclusions:
- S. pseudopneumoniae is an infrequently encountered bacterium in clinical settings.
- Further research is warranted to fully elucidate the clinical significance and pathogenic mechanisms of S. pseudopneumoniae.