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Pigmented villonodular synovitis.

Wakenda K Tyler1, Armando F Vidal, Riley J Williams

  • 1Hospital for Special Surgery, 535 E. 70th Street, New York, NY 10021, USA.

The Journal of the American Academy of Orthopaedic Surgeons
|June 8, 2006
PubMed
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Pigmented villonodular synovitis (PVNS) is a joint condition. Surgical removal (synovectomy) is standard, but the diffuse form has high recurrence rates, potentially requiring joint replacement.

Area of Science:

  • Orthopedics
  • Rheumatology
  • Pathology

Background:

  • Pigmented villonodular synovitis (PVNS) is a proliferative disorder of the synovium.
  • It commonly affects a single joint (monoarticular), presenting as localized or diffuse forms.
  • The knee is the most frequent site, with the diffuse form exhibiting higher recurrence rates.

Purpose of the Study:

  • To review the management strategies for pigmented villonodular synovitis.
  • To discuss the efficacy and recurrence rates associated with different surgical approaches.
  • To explore alternative and combined treatment modalities for PVNS.

Main Methods:

  • Review of existing literature on pigmented villonodular synovitis management.
  • Analysis of surgical techniques including open and arthroscopic synovectomy.

Related Experiment Videos

  • Evaluation of non-surgical and combined treatment options.

    • Main Results:

    • Localized PVNS has an excellent prognosis with surgical management.
    • Diffuse PVNS has a significant recurrence rate (up to 46%) even after surgery.
    • Arthroscopic synovectomy, while popular, shows higher recurrence rates for diffuse PVNS compared to open synovectomy.

    Conclusions:

    • Synovectomy is crucial for preventing secondary osteoarthritis and the need for joint arthroplasty.
    • Recurrence rates, particularly in diffuse PVNS, necessitate consideration of combined or alternative treatments.
    • In some severe cases, total joint arthroplasty may be the definitive treatment for PVNS.