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Updated: Aug 8, 2026

Measurement of Cytosolic Ca2+ in Isolated Contractile Lymphatics
Published on: December 8, 2011
The free cytoplasmic Ca2+ levels in Duchenne muscular dystrophy lymphocytes
A Klip1, B Elder, H P Ruiz-Funes
1Department of Neurology, Research Institute, Hospital for Sick Children, University of Toronto, Ontario, Canada.
Abstract:
An increased cellular Ca2+ content has been associated with Duchenne muscular dystrophy (DMD). However, estimates of the free cytoplasmic Ca2+ concentration ([Ca2+]i) in cells of DMD patients were not available. We compared the [Ca2+]i levels of normal and DMD peripheral blood lymphocytes and Epstein-Barr virus-transformed lymphoblasts using the novel probe, quin 2, an internally trapped fluorescent indicator. The [Ca2+]i levels of normal and DMD cells were not significantly different.
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