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Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues
Published on: October 20, 2019
Diploid partial mole with neonatal survival--a case report
Rachna Agarwal1, Sonika Agarwal, K K Roy
1Department of Obstetrics & Gynaecology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi. rachna_anila@yahoo.co.in
Indian Journal of Pathology & Microbiology
|June 9, 2006
Summary
This study reports a rare case of diploid partial mole, a gestational neoplastic disorder. Despite poor fetal outcomes typically seen, this case resulted in a healthy liveborn infant with no malignant progression.
Area of Science:
- Reproductive Medicine
- Gynecologic Oncology
- Genetics
Background:
- Partial mole is a rare gestational neoplastic disorder, typically presenting with a triploid karyotype.
- Diploid partial moles are exceptionally rare, with limited documented cases and historically poor fetal outcomes.
Observation:
- A case of partial mole was managed, resulting in delivery at 28 weeks.
- The pregnancy yielded a live diploid male fetus.
Findings:
- The liveborn infant exhibited good neonatal outcomes.
- Post-delivery follow-up confirmed no progression to malignant gestational trophoblastic disease.
Implications:
- This case challenges the typical poor fetal prognosis associated with diploid partial moles.
- Highlights the importance of careful monitoring and management in rare gestational trophoblastic diseases.
