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Published on: September 20, 2018
[Matrix stone: a case report].
Masanori Kono1, Akihiro Kato, Kazuto Komatsu
1The Department of Urology, Fukui Red Cross Hospital.
This case study details a rare protein matrix stone in a patient with chronic renal failure, diabetes, and gout. Successful percutaneous removal highlights diagnostic challenges in differentiating matrix stones from tumors.
Area of Science:
- Nephrology
- Urology
- Radiology
Background:
- Matrix stones are rare renal calculi primarily composed of organic material.
- Patients with chronic renal failure, diabetes, and gout may have increased risk.
- Distinguishing matrix stones from urothelial cancers on imaging can be challenging.
Observation:
- A 32-year-old male with diabetes, gout, and chronic renal failure presented with left flank pain.
- History of bilateral vesicoureteral reflux surgery and recurrent matrix stone discharge.
- CT scan showed a soft tissue mass in the right hydroureter.
Findings:
- Percutaneous ureteral lithotripsy was successfully performed.
- Analysis confirmed the stone was composed entirely of protein.
- Radiological features mimicked urothelial carcinoma.
Implications:
- This case underscores the importance of considering protein matrix stones in the differential diagnosis of obstructive ureteral masses.
- Accurate diagnosis is crucial for appropriate management and avoiding unnecessary aggressive treatments.
- Further research into imaging characteristics differentiating matrix stones from malignancies is warranted.
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