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[Study on the correlation of vitamin A and iron status in children]
Jian-hong Li1, Jian-hua Piao, Ning Guo
1Institute for Nutrition and Food Safety, Chinese CDC, Beijing 100050, China.
Insights
Vitamin A (VA) deficiency and marginal deficiency are prevalent in Chinese children, affecting 8.4% and 44.7% respectively. Plasma VA levels correlate with iron status, indicating a coexisting nutritional challenge.
Area of Science:
- Nutritional Science
- Pediatric Health
- Public Health
Background:
- Vitamin A (VA) is crucial for immune function and vision.
- Iron deficiency is a common nutritional problem in children globally.
- Assessing the combined nutritional status is vital for effective public health interventions.
Purpose of the Study:
- To determine vitamin A status in Chinese children.
- To investigate the prevalence of vitamin A deficiency and marginal deficiency.
- To explore the relationship between vitamin A and iron status.
Main Methods:
- Analysis of data from the 2002 Chinese National Health and Nutrition Survey (CNHS).
- Measurement of plasma vitamin A, hemoglobin, ferritin, TIBC, and sTfR in 380 children.
- Statistical analysis to assess deficiency prevalence and correlations.
Main Results:
- The prevalence of vitamin A deficiency was 8.4%, and marginal deficiency was 44.7%.
- Plasma vitamin A showed a positive correlation with hemoglobin (r=0.16986, P<0.01).
- Plasma vitamin A was negatively correlated with soluble transferrin receptor (r=-0.12863, P<0.05), but not with ferritin or TIBC.
Conclusions:
- Vitamin A deficiency and marginal deficiency are widespread among Chinese children.
- Iron deficiency coexists with vitamin A marginal deficiency in this population.
- Plasma vitamin A levels are significantly correlated with key indicators of iron status.
Objective:
To study vitamin A status, the prevalence of vitamin A (VA) deficiency and marginal VA deficiency and the correlation of VA and iron status of Chinese children.
Methods:
380 children were randomly chosen from "Survey on the Status of Nutrition and Health of the Chinese People" (CNHS) in 2002. The plasma vitamin A, hemoglobin (Hb), total iron-binding capacity (TIBC), ferritin (SF) and soluble transferrin receptor (sTfR) were detected. The prevalence of VA deficiency and marginal deficiency was assessed and the correlation of VA and iron indexes was studied.
Results:
The VA concentration of subjects was (1.03 +/- 0.24) micromol/L. The prevalence of VA deficiency and VA marginal deficient was 8.4% and 44.7% respectively. Plasma VA was positively correlated with Hb (r = 0.16986, P < 0.01) and negatively correlated with sTfR (r = -0.12863, P < 0.05) significantly but there was no association of SF and TIBC.
Conclusion:
Iron deficiency coexisted VA marginal deficiency are still very prevalent in Chinese children, plasma VA are correlated with iron status.
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