Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Melanosis intestini: case report.

Anna Batistatou1, John Panelos, Niki J Agnantis

  • 1Department of Pathology, University of Ioannina Medical School, Ioannina, Greece. abatista@cc.uoi.gr

Diagnostic Pathology
|June 9, 2006
PubMed
Summary

Gastrointestinal melanosis, pigment deposits in the gut lining, is rare in the small intestine. This case highlights melanosis in both the colon and terminal ileum linked to stimulant laxative use.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Use of Osteo-Inductive 3D-Printed Scaffolds Covered with a Pleiotrophin Peptide for Bone Defects: An In Vivo Experimental Study.

Bioengineering (Basel, Switzerland)·2026
Same author

Host's immune response to primary tumours and concomitant brain metastases in the central nervous system.

Contemporary oncology (Poznan, Poland)·2026
Same author

The SGLT2 inhibitor empagliflozin exerts neuroprotective effect against hydrogen peroxide-induced toxicity on primary neurons.

Metabolic brain disease·2024
Same author

TAMs and PD-1 Networking in Gastric Cancer: A Review of the Literature.

Cancers·2024
Same author

Ten-year clinical outcome, toxicity and compliance of dose-dense sequential adjuvant administration of cyclophosphamide & epirubicin followed by docetaxel in patients with early breast cancer: A hellenic cooperative oncology group observational study (HE 10/10) with concurrent investigation of significance of tumor infiltrating lymphocytes.

Breast (Edinburgh, Scotland)·2024
Same author

Deep Learning for Lung Cancer Diagnosis, Prognosis and Prediction Using Histological and Cytological Images: A Systematic Review.

Cancers·2023

Area of Science:

  • Gastroenterology
  • Pathology
  • Pharmacology

Background:

  • Melanosis involves pigment deposits in the gastrointestinal (GI) mucosa.
  • Colon melanosis is relatively common, but small intestine melanosis is exceptionally rare.
  • Anthraceneline laxatives are known to cause GI mucosal changes.

Purpose of the Study:

  • To report an extremely rare case of melanosis.
  • To document melanosis occurring in both the colon and terminal ileum.
  • To associate this finding with the use of anthraceneline laxatives.

Main Methods:

  • Case report description.
  • Endoscopic and histopathological examination of the GI tract.
  • Review of patient's medication history.

Main Results:

  • Melanosis observed in the colonic mucosa.
  • Melanosis also identified in the terminal ileum.
  • Findings were associated with the patient's long-term use of anthraceneline laxatives.

Conclusions:

  • Melanosis of the terminal ileum is an extremely rare finding.
  • Anthraceneline laxative use is a potential cause of melanosis in the distal small intestine and colon.
  • Gastroenterologists and pathologists should be aware of this association.

Related Experiment Videos