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[Intertoe space cutaneous epidermoid carcinoma].

Z Terrab1, S Azzouzi, H Benchikhi

  • 1Service de Dermatologie, CHU Ibn Rochd, Casablanca, Maroc. terrabz@megaflex.ma

Annales De Dermatologie Et De Venereologie
|June 9, 2006
PubMed
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Epidermoid carcinoma in the intertoe space is rare, often linked to chronic intertoe intertrigo and maceration. This case highlights the importance of considering this rare cancer in persistent intertoe conditions.

Area of Science:

  • Dermatology
  • Oncology
  • Podiatry

Background:

  • Epidermoid carcinoma (squamous cell carcinoma) rarely occurs in the intertoe spaces.
  • Chronic intertoe intertrigo is a predisposing factor for this rare malignancy.

Observation:

  • A 66-year-old woman presented with a 4-year history of painful ulceration in the 3rd left intertoe space, unresponsive to antifungal treatment.
  • Clinical examination revealed an ulcerated lesion with infiltrated edges, confirmed as epidermoid carcinoma via biopsy.
  • The patient had a 30-year history of chronic intertoe intertrigo.

Findings:

  • Histopathological examination confirmed epidermoid carcinoma.
  • Surgical excision with a 5 mm safety margin and removal of the 3rd and 4th left toes resulted in a favorable outcome with no relapse at 12 months.

Related Experiment Videos

  • Chronic maceration, exacerbated by cultural practices (ritual ablutions) and domestic habits, was identified as a key etiological factor.

    • Implications:

    • This case underscores the rare but significant association between chronic intertoe maceration and the development of epidermoid carcinoma.
    • Early recognition and management of chronic intertoe conditions are crucial to prevent malignant transformation.
    • Cultural and environmental factors can play a significant role in the etiology of intertoe epidermoid carcinoma.