[Effects of osteoporosis on experimental tooth movement in aged rats]
Li-jun Tan1, Jun Wang, Zhi-he Zhao
1Department of Orthodontics, West China Stomatological Hospital, Sichuan University, Chengdu 610041, China.
Objective:
To examine the experimental tooth movement and recruitment of new osteoclasts in aged variotomized (OVX) rats.
Methods:
Eighty-two 3-month female virgin health rats were divided into two groups. Each group was divided into seven sub-groups of tooth movement: 0,1,3,5,7,10 and 14 days. The tooth movement and the population of osteoclasts were measured and comparatively analyzed.
Results:
The osteoporosis rats showed larger and faster tooth movement (P<0.05). In the osteoporosis group, the instantaneous tooth movement lasted longer time and traversed larger distance, the delay period was shorter, the population of osteoclasts was larger and displayed a faster recruitment.
Conclusion:
These findings indicate that osteoporosis accelerates tooth movement in aged OVX rats.
