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Updated: Aug 7, 2026
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Single Oocyte Bisulfite Mutagenesis
Published on: June 27, 2012
Analysis of DNA methylation profiles in preimplantation embryos using bisulfite mutagenesis
Yong-Mahn Han1, Seok-Ho Kim, Yong-Kook Kang
1Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnology, Daejeon.
Methods in Molecular Biology (Clifton, N.J.)
|June 10, 2006
Abstract:
For developmental competence of mammalian embryos, dynamic epigenetic changes to both the maternally and paternally derived contributions to the genome of the zygote should be brought about in the early cleavage stages. DNA methylation is a typical epigenetic mark modified during pre-implantation development. Here, we describe how to analyze DNA methylation profiles in early-stage embryos.
