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Amplifying and Quantifying HIV-1 RNA in HIV Infected Individuals with Viral Loads Below the Limit of Detection by Standard Clinical Assays
Published on: September 26, 2011
HIV-1 infection in early seroconversion stage missed by rapid or ELISA tests--two case reports
Neerja Jindal1, Rajiv Tiwari, Aruna Aggarwal
1Department of Microbiology, Govt. Medical College, Amritsar. jindal_neerja@hotmail.com
Abstract:
Two cases of HIV-1 infection demonstrating lack of sensitivity of rapid and ELISA screening tests are being reported. The first case was that of a 23 years old female whose recent infection was picked up by ELISA (Tetra ELISA) test but missed by two rapid tests (Comb AIDS and HIV Tridot). The 2nd case presumably too in early seroconversion phase, was that of a 39 years old male. In this case ELISA test failed to diagnose the infection while the two rapid tests were found to be strongly positive.
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