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Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
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Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Published on: March 17, 2014

Bacteriological study of paediatric and adult chronic suppurative otitis media

Santosh Saini1, Naveen Gupta, Aparna

  • 1Department of Pathology, Pt. B.D. Sharma PGIMS, Rohtak.

Indian Journal of Pathology & Microbiology
|June 10, 2006
PubMed

Insights

Chronic suppurative otitis media (CSOM) is a common ear infection, particularly in children. This study identified key bacteria and their antibiotic resistance, guiding effective treatment for CSOM.

Area of Science:

  • Otolaryngology
  • Microbiology
  • Infectious Diseases

Background:

  • Chronic suppurative otitis media (CSOM) is a prevalent ENT condition, especially in underserved populations with a history of inadequate medical care.
  • Understanding the microbial etiology and antimicrobial susceptibility patterns is crucial for effective therapeutic strategies in CSOM.

Purpose of the Study:

  • To identify aerobic and anaerobic microorganisms associated with CSOM in pediatric and adult patients.
  • To determine the current antimicrobial susceptibility patterns of these microorganisms to guide treatment decisions for CSOM.

Main Methods:

  • Clinical samples were collected from 109 diagnosed CSOM cases (74 pediatric, 35 adult).
  • Samples were processed using standard microbiological protocols for bacterial culture and identification.
  • Antimicrobial susceptibility testing was performed on isolated microorganisms.

Main Results:

  • Bacterial cultures were positive in 97.2% of pediatric and 80% of adult CSOM cases.
  • CSOM exhibited a polymicrobial nature in both age groups (70.8% pediatric, 71.4% adult).
  • Common isolates included Staphylococcus aureus (pediatric), Pseudomonas aeruginosa (adult), Peptostreptococcus spp. (pediatric anaerobe), and Prevotella melaninogenica (adult anaerobe).
  • High sensitivity was observed for Gram-negative bacilli to cefotaxime (90-100%) and for anaerobes to metronidazole, clindamycin, and chloramphenicol (95.7-98.6%).

Conclusions:

  • CSOM is frequently polymicrobial, necessitating broad-spectrum antimicrobial therapy.
  • Current antimicrobial susceptibility data provides a guide for selecting effective treatments for CSOM.
  • Prompt and appropriate antimicrobial therapy is essential to prevent long-term sequelae of CSOM.

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