Related Experiment Video
Updated: Aug 7, 2026

Bidirectional Electrical and Optoelectronic Interfaces in Healthy and Ischemic Ex Vivo Rat Hearts
Published on: July 18, 2025
The effect of the cut surface during electrical stimulation of a cardiac wedge preparation
Bradley J Roth1, Salil G Patel, Ryan A Murdick
1Department of Physics, Oakland University, Rochester, MI 48309-4487, USA. roth@oakland.edu
Abstract:
Optical mapping from the cut surface of a "wedge preparation" allows observation inside the heart wall, below the epicardium or endocardium. We use numerical simulations based on the bidomain model to illustrate how the transmembrane potential is influenced by the cut surface. The distribution of transmembrane potential around a unipolar cathode depends on the fiber angle. For intermediate angles, hyperpolarization appears on only one side of the electrode, and is large and widespread.
More Related Videos
Related Concept Videos
Cardiac Action Potential
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials
Electrophysiology of Normal Cardiac Rhythm

