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Positive selection in the evolution of cancer

Bernard J Crespi1, Kyle Summers

  • 1Behavioural Ecology Research Group, Department of Biology, Simon Fraser University, Burnaby, BC V5A 1 S6 Canada. crespi@sfu.ca

Biological Reviews of the Cambridge Philosophical Society
|June 10, 2006
PubMed
Summary

Antagonistic coevolution, driven by conflicts like those between sexes or hosts and parasites, may increase cancer risk. Genes involved in these evolutionary conflicts can promote cancer as a secondary effect.

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