Related Experiment Video
Updated: Aug 7, 2026

Control of Eating Behavior Using a Novel Feedback System
Published on: May 8, 2018
The role of CART in body weight homeostasis
Philip J Larsen1, Richard G Hunter
1Rheoscience A/S, The Panum Institute, University of Copenhagen, Glerupvej 2, 2610 Rødovre, Denmark.
Abstract:
Cocaine-amphetamine regulated transcript (CART) was first identified as a complete mRNA transcript 10 years ago. Since then it has been demonstrated that CART is a peptide neurotransmitter which has a role in a number of physiological processes, including body weight homeostasis and energy balance, in a number of vertebrate species. Research to date has demonstrated a role for CART in the control of food intake at a number of levels within the brain of both animals and man.
Related Concept Videos
What is Homeostasis?
Skeleton and Calcium Homeostasis
Positive and Negative Feedback Loops
Regulation of the Cardiovascular System
The regulation of the cardiovascular system involves the autonomic nervous system (ANS), baroreceptors, and chemoreceptors, ensuring that heart rate and blood pressure are appropriately modulated in response to varying physiological demands.
The ANS comprises two main divisions: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system enhances...
Homeostatic Imbalance
However, sometimes these feedback loops fail,...
Primary Motives: Hunger and Thirst
Hunger arises when the brain detects changes in the body's nutrient levels, including glucose, lipids, amino acids, and hormones such as ghrelin and leptin. The hypothalamus plays a central role in hunger regulation. The lateral hypothalamus acts...

