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Updated: Aug 11, 2026

An Improved Method for the Preparation of Type I Collagen From Skin
Published on: January 22, 2014
The effect of various avocado oils on skin collagen metabolism
M J Werman1, S Mokady, M E Nimni
1Department of Food Engineering and Biotechnology, Technion-Israel Institute of Technology, Haifa, Israel.
Abstract:
The effects of various avocado oils on collagen metabolism in skin were studied in growing rats fed diets containing 10% (w/w) of the tested oils. Rats fed the unrefined avocado oil extracted with hexane from the intact fruit, its unsaponifiables or the avocado seed oil, showed significant increases in soluble collagen content in skin, though total collagen content was not affected. The increased soluble collagen content appears to be a consequence of the inhibition of lysyl oxidase activity. The active factor was found to be present in the unrefined avocado oil and probably originated from the avocado seed, since collagen metabolism was affected only by fractions which contained lipids fraction from the seed. In comparison rats fed the refined or unrefined soybean oils showed no effects.
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