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Published on: January 29, 2016
Cognitive and motor function in people with multiple sclerosis in Stockholm County
U Einarsson1, K Gottberg, L von Koch
1Division of Physiotherapy, Neurotec Department, Karolinska Institutet, S-141 86 Stockholm, Sweden. ulrika.einarsson@karolinska.se
Summary
Cognitive and motor functions in people with multiple sclerosis (PwMS) were analyzed. Lower disability and higher education correlated with better cognitive function, while employment predicted better motor skills.
Area of Science:
- Neurology
- Neuroscience
- Rehabilitation Medicine
Background:
- Multiple Sclerosis (MS) is a chronic neurological disease affecting cognitive and motor functions.
- Understanding factors influencing these functions is crucial for patient management and rehabilitation.
Purpose of the Study:
- To analyze cognitive and motor function in a population-based sample of people with multiple sclerosis (PwMS).
- To investigate the influence of disease-related data and sociodemographic factors on these functions.
Main Methods:
- 166 PwMS were assessed using various cognitive tests (MMSE, FRR12RWT, SDMT) and motor function assessments (NHPT, Lindmark Motor Capacity Assessment, 10-metre walk).
- Disease severity and sociodemographic data (education, employment) were collected.
Main Results:
- Approximately half of PwMS scored within the normal range on cognitive tests.
- A minority demonstrated normal manual dexterity (27%), maximal motor capacity (9%), and normal walking speed (8%).
- Lower disability and higher education were associated with normal cognitive function; lower disability and employment predicted normal motor function (NHPT, 10-metre walk).
Conclusions:
- Cognitive function is preserved in about half of PwMS, while motor function is often impaired.
- Both disease severity and sociodemographic factors significantly influence cognitive and motor performance in MS.
- These findings highlight the need for personalized rehabilitation strategies considering individual patient profiles.

