Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Refractive lens exchange in keratoconus.

Antonio Leccisotti1

  • 1Ophthalmic Surgery Unit, Casa di Cura Rugani, Siena, Italy. leccisotti@libero.it

Journal of Cataract and Refractive Surgery
|June 13, 2006
PubMed
Summary

Refractive lens exchange effectively corrected myopia in early keratoconus, but ultrasound biometry accuracy was a concern. Intraoperative autorefractometry is recommended for improved outcomes in these patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preoperative CDVA in KLEx Platforms Performance Evaluation [Letter].

Clinical ophthalmology (Auckland, N.Z.)·2025
Same author

Optical Coherence Tomography in Infectious Keratitis After Femtosecond Keratorefractive Surgery.

Journal of clinical medicine·2025
Same author

Femtosecond LASIK Retreatments After Primary Myopic Photorefractive Keratectomy.

Cornea·2023
Same author

Change in Stromal Thickness and Anterior Curvature After Refractive Corneal Lenticule Extraction With the CLEAR Application.

Journal of refractive surgery (Thorofare, N.J. : 1995)·2022
Same author

Refractive Corneal Lenticule Extraction on Previous Photorefractive Keratectomy, with Optical Coherence Tomography Study.

Case reports in ophthalmology·2022
Same author

Refractive Corneal Lenticule Extraction With the CLEAR Femtosecond Laser Application.

Cornea·2022

Area of Science:

  • Ophthalmology
  • Refractive Surgery
  • Corneal Diseases

Background:

  • Keratoconus is a progressive corneal ectasia often requiring refractive correction.
  • Myopia in early-stage keratoconus presents a surgical challenge.
  • Refractive lens exchange (RLE) offers a potential solution for myopia correction in these patients.

Purpose of the Study:

  • To assess the visual outcomes and complications of RLE for myopia in early-stage keratoconus (Stages I-II).
  • To evaluate the accuracy of preoperative biometry and the impact on refractive outcomes.

Main Methods:

  • Prospective interventional study of 34 eyes from 20 patients with early keratoconus.
  • Preoperative assessment included videokeratography and ultrasound biometry with Holladay 2 formula.
  • Intraocular lens (IOL) power was verified using an intraoperative handheld autorefractor.

Main Results:

  • RLE achieved significant improvement in best spectacle-corrected visual acuity (BSCVA).
  • Mean spherical equivalent (SE) postoperatively was -1.31 D; 47% achieved within +/-1 D of target.
  • IOL exchange was needed in 32% of eyes due to inaccurate power; intraoperative autorefractometry is advised.

Conclusions:

  • RLE can predictably correct myopia in eyes with early keratoconus.
  • Ultrasound biometry demonstrated significant inaccuracy in nearly one-third of cases.
  • Intraoperative autorefractometry is crucial for optimizing refractive outcomes in RLE for keratoconus.

Related Experiment Videos