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Toll-like receptor 2-mediated human B cell differentiation.

Lisa M Ganley-Leal1, Xiuping Liu, Lee M Wetzler

  • 1Department of Medicine, Boston Medical Center, Boston University School of Medicine, Evans Biomedical Research Center, 650 Albany Street, Boston, MA 02118, USA. Lisa.ganleyleal@bmc.org

Clinical Immunology (Orlando, Fla.)
|June 13, 2006
PubMed
Summary

Toll-like receptor 2 (TLR2) agonists activate human B cells, promoting germinal center formation and IgM secretion. This suggests TLR2 is a potential vaccine adjuvant target for enhancing immune responses.

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