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Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Previous percutaneous coronary intervention may increase symptom recurrence and adverse cardiac events following
Ahmet Tayfun Gürbüz1, Ahmet Saşmazel, Haiyan Cui
1Department of Cardiovascular Surgery and Cardiology, Tucson Medical Center, Tucson, AZ, USA. tayfun.gurbuz@anadolusaglik.org
Insights
Patients with prior percutaneous coronary interventions (PCI) face higher risks of symptom recurrence and adverse cardiovascular events after coronary artery bypass graft (CABG) surgery. Restenosis after PCI further increases these negative outcomes.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
Background:
- Percutaneous coronary interventions (PCI) are increasingly common.
- Limited data exists on outcomes for patients needing surgical revascularization after PCI.
Purpose of the Study:
- To determine if preoperative PCI is a risk factor for symptom recurrence, adverse cardiovascular events, and mortality after coronary artery bypass graft (CABG) surgery.
- To compare outcomes between patients with and without a history of PCI undergoing CABG.
Main Methods:
- Retrospective evaluation of 611 patients who survived 30 days post-CABG (2001-2005).
- Mean follow-up of 29.4 months.
- Analysis of preoperative PCI as a risk factor for outcomes.
Main Results:
- Preoperative PCI independently predicted increased symptom recurrence (p<0.0001) and adverse cardiac events (p<0.0001).
- Patients with prior PCI had significantly worse outcomes compared to those without.
- History of restenosis post-PCI correlated with more adverse endpoints (p<0.0001).
Conclusions:
- Patients with prior PCI are more prone to symptom recurrence and adverse cardiovascular events post-CABG.
- The negative impact is amplified in patients experiencing restenosis after PCI.
Objective:
The number of percutaneous coronary interventions (PCI) is increasing. There is limited outcome data on patients with a history of PCI and subsequently required surgical revascularization.
Methods:
Overall 611 patients who survived 30 days after coronary artery bypass graft surgery (CABG) between 2001 and 2005 were evaluated. Mean follow-up was 29.4 +/- 11.3 months and 45% were female. The effect of preoperative PCI as a risk factor for symptom recurrence and adverse cardiovascular events and mortality was determined.
Results:
Preoperative PCI was an independent risk factor for symptom recurrence (p<0.0001), combined adverse cardiac events (p<0.0001) and slightly increased overall mortality (p<0.04). Comparison of patients with and without a prior PCI showed that former had significantly worse outcomes compared to the latter. Patients with history of at least one restenosis following a PCI developed significantly more adverse end points (p<0.0001).
Conclusion:
In this study, patients with previous PCI were more likely to develop symptom recurrence and adverse cardiovascular events following CABG. This difference was more pronounced in patients who had at least one recurrent stenosis after a PCI.
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