Gardner-Diamond syndrome with multiple glomus tumors

Area of Science:

• Dermatology
• Hematology

Background:

• Multiple glomus tumors are rare benign neoplasms.
• Gardner-Diamond syndrome is a rare bleeding disorder characterized by painful purpura.

Purpose of the Study:

• To report a unique case of a patient presenting with both multiple glomus tumors and Gardner-Diamond syndrome.
• To describe the diagnostic confirmation of both conditions.

Main Methods:

• Diagnosis of multiple glomus tumors confirmed via histopathological examination (biopsy).
• Diagnosis of Gardner-Diamond syndrome confirmed by reproducing painful purpura via intradermal injection of sonicated autologous erythrocytes.

Main Results:

• Histopathological analysis confirmed the presence of multiple glomus tumors.
• Intradermal injection of sonicated erythrocytes successfully induced painful purpura, confirming Gardner-Diamond syndrome.

Conclusions:

• This case highlights the rare co-occurrence of multiple glomus tumors and Gardner-Diamond syndrome.
• The diagnostic methods employed were effective in confirming both unusual dermatologic and hematologic entities.