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Updated: Aug 7, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Visual recovery following Mycobacterium chelonae endophthalmitis
Michael W Stewart1, Salvador Alvarez, William W Ginsburg
1Department of Ophthalmology, Mayo Clinic College of Medicine, Jacksonville, FL 32224, USA. stewart.michael@mayo.edu
Abstract:
Following uncomplicated cataract surgery, a patient receiving etanercept for psoriatic arthritis developed Mycobacterium chelonae endophthalmitis. Vitrectomy, capsulectomy, and intraocular lens removal was followed by intravitreal amikacin, topical gatifloxacin, intravenous imipenem, and oral clarithromycin for six months. The patient achieved a final corrected visual acuity of 20/20. Etanercept has been implicated in the development of numerous, severe granulomatous infections, though not previously with M. chelonae. This represents the first reported case of visual recovery following M. chelonae endophthalmitis.
