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When cluster headache was called histaminic cephalalgia (Horton's headache)
1Department of Internal Medicine, University of Florence, Viale G. Pieraccini 18, I-50139, Firenze, Italy. fanciullac.marcello@tiscalinet.it
This article reviews historical research on histaminic cephalalgia, now known as cluster headache (CH). Early work suggested brain involvement in CH, paving the way for current understanding and future treatments.
Area of Science:
- Neurology
- Neuroscience
- Headache Medicine
Background:
- Recounts historical research and clinical experiences with "histaminic cephalalgia" (Horton's headache).
- Highlights the pioneering contributions of the Florence School in early headache research.
- Establishes context for understanding the evolution of cluster headache (CH) knowledge.
Observation:
- Details the early conceptualization of histaminic cephalalgia.
- Discusses the author's personal involvement in frontline research and clinical practice.
- Emphasizes the historical perspective on a condition now recognized as cluster headache.
Findings:
- Presents an outline of early research contributions.
- Promotes research into the potential brain involvement in cluster headache (CH) pathogenesis.
- Connects historical insights to the current worldwide acceptance of brain involvement in CH.
Implications:
- Suggests that recent progress in CH research is unraveling its mysteries.
- Anticipates future advancements in patient education and treatment strategies.
- Aims to minimize patient suffering through improved understanding and management of CH.
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