Related Experiment Video
Updated: May 22, 2026
10:39
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Italian guidelines for primary headaches: 2012 revised version
Paola Sarchielli1, Franco Granella, Maria Pia Prudenzano
1Headache Centre, Neurologic Clinic, University of Perugia, Perugia, Italy. paola.sarchielli@gmail.com
The Journal of Headache and Pain
|May 15, 2012
Summary
This study updates Italian guidelines for primary headache treatments, incorporating new research from 2001-2011. It provides revised recommendations for migraine and cluster headache management, including non-pharmacological options.
Area of Science:
- Neurology
- Clinical Guideline Development
Background:
- The Italian Society for the Study of Headaches (SISC) previously published guidelines for primary headaches in adults in 2001.
- A decade later, an update was deemed necessary to incorporate advancements in headache treatment.
Purpose of the Study:
- To revise and update the diagnostic and therapeutic guidelines for primary headaches in adults.
- To provide evidence-based recommendations for symptomatic and prophylactic treatments.
Main Methods:
- A comprehensive literature search was conducted on the Medline database for studies published between February 2001 and December 2011.
- Analysis focused on randomized controlled trials (RCTs) and meta-analyses, with open studies and case series considered if RCTs were unavailable.
- Recommendations were categorized using four levels based on evidence, scientific strength, and clinical effectiveness.
Main Results:
- Recommendations for symptomatic and prophylactic treatments for migraine and cluster headache were revised.
- A new section was added to address non-pharmacological treatment options.
- The updated guidelines reflect the latest scientific evidence and clinical practice.
Conclusions:
- The revised guidelines offer an updated framework for managing primary headaches in adults.
- These updated SISC guidelines aim to improve patient care through evidence-based recommendations.
Related Concept Videos
01:14Increased Intracranial Pressure l: Introduction
Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
01:29Increased Intracranial Pressure ll: Pathophysiology
Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...
01:10Pre-Procedural Guidelines for Assessing Blood Pressure
Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the patient.
01:30Hypertension III: Clinical Manifestations and Diagnostic Studies
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...