Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Late onset psychogenic nonepileptic attacks.

Roderick Duncan1, Meritxell Oto, Emma Martin

  • 1West of Scotland Regional Epilepsy Service, Institute of Neurological Sciences, Southern General Hospital, Glasgow, Scotland.

Neurology
|June 14, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unplanned placement changes in children's homes: an observational study of national administrative data on children in care and providers in England.

BMJ public health·2026
Same author

Monolithic manufacturing of an electrically addressable quasi-suspended nanophotonic aperture.

Nature nanotechnology·2026
Same author

Microstructural disease and hypoperfusion in dilated cardiomyopathy underpin midwall septal fibrosis.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance·2026
Same author

Mechanical characterization of Bi-2212 composite winding pack samples for high-field superconducting magnet design.

Superconductor science & technology·2026
Same author

Incidental findings and duty-of-care protocols in cardiovascular magnetic resonance among older adults: a prospective population-based study from MyoFit46.

The lancet. Healthy longevity·2026
Same author

Emerging radar-based technologies for cuffless blood pressure monitoring-a systematic review.

The Lancet. Digital health·2026
Same journal

Factors Associated With Disability Improvement and Worsening Independent of Attacks in Patients With AQP4-IgG+ NMOSD and MOGAD: A Multicenter Cohort Study.

Neurology·2026
Same journal

Cost-Effectiveness of Intracranial Aneurysm Screening: A Systematic Review.

Neurology·2026
Same journal

Rare Eating Epilepsy: Co-Occurrence of Focal Cortical Dysplasia and Gray Matter Heterotopia.

Neurology·2026
Same journal

Spatiotemporal Associations Between Cortical Microinfarcts and Cortical Superficial Siderosis in Cerebral Amyloid Angiopathy.

Neurology·2026
Same journal

Blood-Brain Barrier Disruption Before Interhospital Transfer for Thrombectomy and Clinical Outcome.

Neurology·2026
Same journal

At Death's Door: Cytosolic Dopamine in Patients With Parkinson Disease.

Neurology·2026
See all related articles

Late-onset psychogenic nonepileptic attacks (PNEA) appear distinct, often linked to severe physical health issues and trauma, unlike early-onset PNEA. This suggests a unique patient subgroup requiring tailored care.

Area of Science:

  • Neurology
  • Psychiatry
  • Psychosomatic Medicine

Background:

  • Psychogenic nonepileptic attacks (PNEA) are paroxysmal events resembling epileptic seizures but without underlying epilepsy.
  • Understanding PNEA onset variations is crucial for diagnosis and management.
  • Late-onset PNEA (after age 55) may represent a distinct clinical entity compared to earlier onset.

Purpose of the Study:

  • To delineate the characteristics differentiating early-onset from late-onset psychogenic nonepileptic attacks (PNEA).
  • To identify specific sociodemographic, predisposing, clinical, and background factors associated with PNEA onset timing.

Main Methods:

  • Comparative analysis of patients with PNEA onset before age 55 (n=241) versus after age 55 (n=26).
  • Assessment of sociodemographic variables, predisposing factors, clinical semiology, and medical/psychiatric history.

Related Experiment Videos

  • Statistical comparison of characteristics between the early-onset and late-onset PNEA groups.

    • Main Results:

    • Late-onset PNEA patients were more frequently male and less likely to report a history of sexual abuse.
    • Severe physical health problems and health-related trauma were significantly more common in the late-onset PNEA group.
    • No significant differences in PNEA clinical semiology were observed; a trend towards better baseline mental health in the late-onset group was noted.

    Conclusions:

    • The findings suggest a distinct subgroup of patients experiencing late-onset psychogenic nonepileptic attacks.
    • Psychological trauma associated with severe physical health problems appears to be a key factor in late-onset PNEA.
    • This distinct subgroup may benefit from targeted therapeutic approaches addressing physical health and trauma.