Related Experiment Video
Updated: Jun 14, 2026

Metabolic Profiling to Determine Bactericidal or Bacteriostatic Effects of New Natural Products using Isothermal Microcalorimetry
Published on: October 29, 2020
Electrochemical characteristics of gatifloxacin and its interaction with DNA
1Department of Chemistry, Zhejiang Forestry University, LinAn, China. tdky@hotmail.com
Abstract:
The electrochemical behavior of gatifloxacin (GTFX) and its interaction with natural calf thymus DNA (ctDNA) is investigated by differential pulse voltammetry (DPV) on a carbon paraffined electrode. According to the suggested electrochemical equation, a binding constant of 1.7058 x 10(5) (mol L(-1))(-1) and binding sizes s = 3.09 (base pairs) of GTFX with ctDNA are obtained by nonlinear fit analysis of electrochemical data. The results demonstrate that GTFX has the properties of an intercalative binder.
Related Concept Videos
DNA Base Pairing
Drug-Receptor Bonds
In...
Inhibitors of Bacterial Protein Synthesis
Inhibitors of Bacterial DNA Synthesis

