Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Normative reference values for lung transfer factor in Isfahan, Iran.

Babak Amra1, Mehrnaz Asadi, Hassan Salehi

  • 1Isfahan University of Medical Sciences, Isfahan, Iran. amra@med.mui.ac.ir

Respirology (Carlton, Vic.)
|June 15, 2006
PubMed
Summary

This study developed new predictive equations for carbon monoxide diffusing capacity (DL(CO)) and its volume-corrected form (DL(CO)/VA) in a large Iranian population. These equations, based on age and height, provide a reference frame for gas exchange assessment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluating the Validity of Sleep Disturbance Scale for Children in Attention-deficit/Hyperactivity Disorder.

Basic and clinical neuroscience·2026
Same author

Computed tomography of interstitial lung disease in systemic sclerosis: dataset and deep learning model for pulmonary lesion segmentation.

Reumatismo·2026
Same author

Continuous positive airway pressure treatment for sleep apnea in elderly patients systematic review and meta-analysis.

Sleep & breathing = Schlaf & Atmung·2025
Same author

Is Non-Invasive Ventilation a Good Choice in All Patients with Severe COVID-19? A Cohort Retrospective Study.

Tanaffos·2025
Same author

Optimizing In Vitro Propagation of <i>Haworthia truncata</i> Schönland Using Leaf, Root, and Inflorescence.

Plants (Basel, Switzerland)·2025
Same author

Examining the nonlinear effects of traffic and built environment factors on the traffic safety of cyclist from different age groups.

Accident; analysis and prevention·2024

Area of Science:

  • Pulmonary Physiology
  • Respiratory Medicine
  • Clinical Diagnostics

Background:

  • Carbon monoxide diffusing capacity (DL(CO)) assesses gas exchange across the alveolocapillary membrane.
  • DL(CO) and its volume-corrected derivative (DL(CO)/VA) are crucial for evaluating lung function.

Purpose of the Study:

  • To derive gender-specific predictive equations for DL(CO) and DL(CO)/VA.
  • To establish reference values for a large, non-smoking Iranian population using a single-breath method.

Main Methods:

  • 1429 non-smoking subjects (aged 5-85 years) were evaluated.
  • Multiple regression analysis was used to develop gender-specific linear prediction equations.
  • DL(CO) and DL(CO)/VA were regressed against age, height, and body surface area.

Related Experiment Videos

Main Results:

  • Age negatively impacted DL(CO) and DL(CO)/VA in both genders.
  • Height positively influenced DL(CO) and DL(CO)/VA in both genders (P < 0.01).
  • Specific prediction equations were derived for men and women.

Conclusions:

  • The study provides original, gender-specific predictive equations for DL(CO) and DL(CO)/VA in the Iranian population.
  • These equations, derived from a standardized single-breath technique, offer a valuable reference frame.
  • The findings aid in the accurate assessment of gas exchange in this demographic.