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Microalbuminuria: association with ischaemic heart disease in non-diabetics

Rizwan Hashim1, Shazia Nisar, Khalil ur Rehman

  • 1Department of Pathology, Combined Military Hospital, Lahore.

Journal of Ayub Medical College, Abbottabad : JAMC
|June 16, 2006
PubMed

Insights

Microalbuminuria (MA) is common in non-diabetic patients with ischemic heart disease (IHD). This study found MA in 37% of patients, with higher levels observed in older individuals.

Area of Science:

  • Cardiology
  • Nephrology
  • Internal Medicine

Background:

  • Ischemic heart disease (IHD) poses significant morbidity and mortality risks.
  • Assessing individual cardiovascular risk beyond traditional factors like hypertension and hypercholesterolemia is crucial for effective prevention and treatment.
  • Microalbuminuria (MA) is being investigated as a potential marker for IHD in non-diabetic individuals.

Purpose of the Study:

  • To determine the frequency of microalbuminuria (MA) in non-diabetic patients diagnosed with ischemic heart disease (IHD).
  • To investigate the association between MA and age in this patient cohort.

Main Methods:

  • A descriptive study was conducted on 100 consecutive non-diabetic patients with IHD.
  • Patients with clinical albuminuria or other causes of proteinuria were excluded.
  • Urinary albumin was quantified using immunoturbidimetry, and the albumin-to-creatinine ratio (ACR) was calculated.

Main Results:

  • Microalbuminuria (ACR >30 mg/g) was detected in 37% of the non-diabetic IHD patients.
  • The frequency of MA was highest in older age groups for both males and females.
  • A significant difference in mean MA levels was observed across different age groups.

Conclusions:

  • Microalbuminuria is a prevalent finding in non-diabetic patients suffering from ischemic heart disease.
  • Older age is associated with higher mean levels of microalbuminuria in this population.
  • MA may serve as a valuable indicator for cardiovascular risk assessment in non-diabetic IHD patients.
Abstract

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