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Updated: Aug 7, 2026

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
Eccrine angiomatous hamartoma with elements of an arterio-venous malformation: a newly recognized variant
Andy J Chien1, Maryam Asgari, Zsolt B Argenyi
1Division of Dermatology, University of Washington, Seatlle, WA 98195, USA.
Abstract:
We present the case of a 54-year-old man with a brown-red nodule on the hand that had been present since early adulthood. Histology of the excisional biopsy revealed hyperplasia and proliferation of eccrine, apocrine, lipomatous, and vascular structures. These findings were most characteristic of the entity known as eccrine angiomatous hamartoma (EAH), an uncommon tumor that may present variable clinical and histological features. In addition, this particular case exhibited a prominent component of arterio-venous malformation that distinguishes it from other EAHs described in the literature and adds to the spectrum of histologic findings that can be seen with this entity.
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